WHSC2 antibody (Center)

Catalog No. ABIN2798759

The Rabbit Polyclonal anti-WHSC2 antibody is suitable to detect WHSC2 in samples from Human. It has been validated for WB.

Quick Overview for WHSC2 antibody (Center) (ABIN2798759)

Target: WHSC2 (Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WHSC2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-WHSC2 Antibody

Binding Specificity: AA 251-279, Center

Purpose: Rabbit Anti-Human WHSC2 (Center) Antibody

Immunogen: This WHSC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 251-279 amino acids from the Central region of human WHSC2.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot
Recommended Dilutions
WB: 1:1000WHSC2 Antibody (Center) .

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for WHSC2

Target: WHSC2 (Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2))

Alternative Name: WHSC2

Background:

Target Description: This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93 % sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation.

Gene Symbol: NELFA

Molecular Weight: 57277 Da

Gene ID: 7469

UniProt: Q9H3P2

Pathways: Chromatin Binding