PCGF2 antibody (Center)

Catalog No. ABIN2798813

Product Details anti-PCGF2 Antibody

Target: PCGF2 (Polycomb Group Ring Finger 2 (PCGF2))

Binding Specificity: AA 121-150, Center

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCGF2 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit Anti-Human PCGF2 (Center) Antibody

Immunogen: This PCGF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 121-150 amino acids from the Central region of human PCGF2.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot
Recommended Dilutions
WB: 1:1000PCGF2 Antibody (Center) .

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.450 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for PCGF2

Target: PCGF2 (Polycomb Group Ring Finger 2 (PCGF2))

Alternative Name: PCGF2 (PCGF2 Products)

Synonyms: ZNF144 antibody, PCGF2 antibody, MEL-18 antibody, RNF110 antibody, Mel18 antibody, Rnf110 antibody, Zfp144 antibody, mel-18 antibody, polycomb group ring finger 2 antibody, PCGF2 antibody, Pcgf2 antibody

Background:

Target Description: The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryogenesis, cell cycles, and tumorigenesis. This protein was shown to act as a negative regulator of transcription and has tumor suppressor activity. The expression of this gene was detected in various tumor cells, but is limited in neural organs in normal tissues. Knockout studies in mice suggested that this protein may negatively regulate the expression of different cytokines, chemokines, and chemokine receptors, and thus plays an important role in lymphocyte differentiation and migration, as well as in immune responses.

Gene Symbol: PCGF2

Molecular Weight: 37788 Da

Gene ID: 7703

UniProt: P35227

Pathways: Chromatin Binding