GLRB antibody (N-Term)

Catalog No. ABIN2798821

This Rabbit Polyclonal antibody specifically detects GLRB in WB. It exhibits reactivity toward Human.

Quick Overview for GLRB antibody (N-Term) (ABIN2798821)

Target: GLRB (Glycine Receptor, beta (GLRB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLRB antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GLRB Antibody

Binding Specificity: AA 103-132, N-Term

Purpose: Rabbit Anti-Human GLRB (N-term) Antibody

Immunogen: This GLRB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-132 amino acids from the N-terminal region of human GLRB.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot
Recommended Dilutions
WB: 1:1000Western blot analysis of lysate from Jurkat cell line, using GLRB Antibody (N-term) at 1:5000 dilution was used as the secondary antibody. Lysate at 35 μg per lane.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for GLRB

Target: GLRB (Glycine Receptor, beta (GLRB))

Alternative Name: GLRB

Background:

Target Description: This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants.

Gene Symbol: GLRB

Molecular Weight: 56122 Da

Gene ID: 2743

UniProt: P48167