DIAPH3 antibody (C-Term)
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- Target See all DIAPH3 Antibodies
- DIAPH3 (Diaphanous Homolog 3 (Drosophila) (DIAPH3))
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Binding Specificity
- AA 1061-1090, C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This DIAPH3 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purpose
- Rabbit Anti-Human DIAPH3 (C-term) Antibody
- Immunogen
- This DIAPH3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1061-1090 amino acids from the C-terminal region of human DIAPH3.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product DIAPH3 Primary Antibody
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- Application Notes
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Western Blot
Recommended Dilutions
WB: 1:1000DIAPH3 Antibody (C-term) . - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Storage
- 4 °C,-20 °C
- Storage Comment
- 2-8°C (short-term), -20°C (long-term)
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- Target
- DIAPH3 (Diaphanous Homolog 3 (Drosophila) (DIAPH3))
- Alternative Name
- DIAPH3 (DIAPH3 Products)
- Synonyms
- Diap3 antibody, DIAP3 antibody, DIAPH3 antibody, 4930417P13Rik antibody, Dia2 antibody, Diaph3 antibody, Drf3 antibody, mDia2 antibody, mKIAA4117 antibody, p134MDia2 antibody, AN antibody, AUNA1 antibody, DIA2 antibody, DRF3 antibody, NSDAN antibody, diap3 antibody, diaphanous-related formin 3 antibody, diaphanous related formin 3 antibody, diaphanous homolog 3 (Drosophila) antibody, Diaph3 antibody, DIAPH3 antibody
- Background
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Target Description: DIAPH3 binds to GTP-bound form of Rho and to profilin. Acts in a Rho-dependent manner to recruit profilin to the membrane, where it promotes actin polymerization. It is required for cytokinesis, stress fiber formation, and transcriptional activation of the serum response factor. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics (By similarity).
Gene Symbol: DIAPH3
- Molecular Weight
- 136926 Da
- Gene ID
- 81624
- UniProt
- Q9NSV4
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