IRS1 antibody (pSer312)

Catalog No. ABIN7302992

This Rabbit Polyclonal antibody specifically detects IRS1 in WB, IF and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for IRS1 antibody (pSer312) (ABIN7302992)

Target: IRS1 (Insulin Receptor Substrate 1 (IRS1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details anti-IRS1 Antibody

Binding Specificity: pSer312

Purpose: Rabbit polyclonal antibody to IRS1 (Phospho-S312)

Specificity: Recognizes endogenous levels of IRS1 protein only when phosphorylated at S312.

Characteristics: Rabbit polyclonal antibody to IRS1 (pS312)

Purification: The antibody was purified by immunogen affinity chromatography.

Immunogen: KLH-conjugated synthetic phosphopeptide corresponding to residues surrounding S312 of human IRS1 protein. The exact sequence is proprietary.

Application Details

Application Notes: WB (1/500 - 1/1000), IF/IC (1/100 - 1/500), IP (1/10 - 1/100)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in 0.42 % Potassium phosphate, 0.87 % Sodium chloride, pH 7.3, 30 % glycerol, and 0.01 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

Expiry Date: 12 months

Target Details for IRS1

Target: IRS1 (Insulin Receptor Substrate 1 (IRS1))

Alternative Name: IRS1

Background: Insulin receptor substrate 1, IRS-1

Gene ID: 3667, 16367, 25467

UniProt: P35568

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Negative Regulation of Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process