MAP2K3 antibody (pThr222) (AbBy Fluor® 594)

Catalog No. ABIN2804123

This Rabbit Polyclonal antibody specifically detects MAP2K3 in WB, IF (cc) and IF (p). It exhibits reactivity toward Mouse.

Quick Overview for MAP2K3 antibody (pThr222) (AbBy Fluor® 594) (ABIN2804123)

Target: MAP2K3 (Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP2K3 antibody is conjugated to AbBy Fluor® 594

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-MAP2K3 Antibody (AbBy Fluor® 594)

Binding Specificity: pThr222

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Cow,Sheep,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human MEK3 around the phosphorylation site of Thr222

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MAP2K3

Target: MAP2K3 (Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3))

Alternative Name: MEK3

Background:

Synonyms: Dual specicity mitogen-activated protein kinase kinase 3, MAP kinase kinase 3, map2k3, MAPK ERK kinase 3, MAPK/ERK kinase 3, MAPKK 3, MAPKK3, MEK 3, MEK3, Mitogen activated protein kinase kinase 3, MKK3, MP2K3_HUMAN, PRKMK3.

Background: Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38.

Gene ID: 5606

Pathways: MAPK Signaling, TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagy, Signaling Events mediated by VEGFR1 and VEGFR2