Fibrinogen antibody (AbBy Fluor® 594)

Catalog No. ABIN2814576

Product Details anti-Fibrinogen Antibody (AbBy Fluor® 594)

Target: Fibrinogen

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This Fibrinogen antibody is conjugated to AbBy Fluor® 594

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Purification: Purified by Protein A.

Immunogen: Fibrinogen from human plasma

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 4°C

Expiry Date: 12 months

Target Details for Fibrinogen

Target: Fibrinogen

Alternative Name: Human Fibrinogen (Fibrinogen Products)

Background:

Fibrinogen is the main protein of blood coagulation system. It is a large protein and it consists of two identical subunits that contain three polypeptide chains: alpha, beta and gamma. All chains are connected with each other by a number of disulfide bonds. Fibrinopeptides A (1 to 16 amino acids) and B (1 to 17 amino acids) are released by thrombin from the N terminal parts of alpha and beta chains, respectively. In this way fibrinogen is converted into fibrin, which by means of polymerization forms a fibrin clot. Fibrinogen clotting underlies pathogenesis of MI, thromboembolism and thromboses of arteries and veins, since fibrin is the main substrate for thrombus formation. Fibrinogen activation is also involved in pathogenesis of inflammation, tumor growth and many other diseases.

Synonyms: FGA, FGA protein, FGB, FGG, Fib2, Fibrin alpha chain ,Fibrinogen A alpha polypeptide, Fibrinogen A alpha polypeptide chain, Fibrinogen alpha chain, Fibrinogen B alpha polypeptide, Fibrinogen beta chain, Fibrinogen G alpha polypeptide, Fibrinogen gamma chain, MGC104327, MGC119422, MGC119423, MGC119425, MGC120405, FIBA_HUMAN.

Gene ID: 2243