p300 antibody (pSer1834)

Catalog No. ABIN389698

This Rabbit Polyclonal antibody specifically detects p300 in IHC (p) and DB. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for p300 antibody (pSer1834) (ABIN389698)

Target: p300 (EP300) (E1A Binding Protein P300 (EP300))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This p300 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Dot Blot (DB)

Clone: RB08095

Product Details anti-p300 Antibody

Binding Specificity: pSer1834

Specificity: This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1834 of human P300.

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This P300 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1834 of human P300.

Isotype: Ig Fraction

Application Details

Application Notes: IHC (p) = 1:10-50, DB = 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-p300 antibody (ABIN389698)

Aubry, Shin, Crary, Lefort, Qureshi, Lefebvre, Califano, Shelanski: "Assembly and interrogation of Alzheimer's disease genetic networks reveal novel regulators of progression." in: PLoS ONE, Vol. 10, Issue 3, pp. e0120352, (2015) (PubMed).

Target Details for p300

Target: p300 (EP300) (E1A Binding Protein P300 (EP300))

Alternative Name: P300

Background: Synonyms: Histone acetyltransferase p300, EC 2.3.1.48, E1A-associated protein p300, EP300, P300

Molecular Weight: 264144 DA

Gene ID: 2033

UniProt: Q09472

Pathways: p53 Signaling, Notch Signaling, Interferon-gamma Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Regulation of Cell Size