HADHA antibody (C-Term)

Catalog No. ABIN390869

The Rabbit Polyclonal anti-HADHA antibody is suitable to detect HADHA in samples from Human. It has been validated for WB, FACS and IHC (p).

Quick Overview for HADHA antibody (C-Term) (ABIN390869)

Target: HADHA (Hydroxyacyl-Coenzyme A Dehydrogenase/3-Ketoacyl-Coenzyme A Thiolase/enoyl-Coenzyme A Hydratase (Trifunctional Protein), alpha Subunit (HADHA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HADHA antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB20987

Product Details anti-HADHA Antibody

Binding Specificity: AA 737-763, C-Term

Specificity: This HADHA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 734~763 amino acids from the C-terminal region of human HADHA.

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HADHA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 737-763 AA from the C-terminal region of human HADHA.

Isotype: Ig Fraction

Application Details

Application Notes: WB = 1:1000, IHC (p) = 1:10-50, FACS = 1:10-50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for HADHA

Target: HADHA (Hydroxyacyl-Coenzyme A Dehydrogenase/3-Ketoacyl-Coenzyme A Thiolase/enoyl-Coenzyme A Hydratase (Trifunctional Protein), alpha Subunit (HADHA))

Alternative Name: HADHA

Background: HADHA is the alpha subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the alpha subunit catalyzing the 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities.
Synonyms: Trifunctional enzyme subunit alpha, mitochondrial, TP-alpha, 78 kDa gastrin-binding protein, Long-chain enoyl-CoA hydratase, Long chain 3-hydroxyacyl-CoA dehydrogenase, HADH, HADHA
Pathways: Fatty acid metabolism, beta-Alanine metabolism, Valine, leucine and isoleucine degradation, Tryptophan metabolism, Biosynthesis of unsaturated fatty acids

Molecular Weight: 83000 Da

Gene ID: 3030

UniProt: P40939

Pathways: Monocarboxylic Acid Catabolic Process