HADHA antibody (AA 484-763)

Catalog No. ABIN6141586

This Rabbit Polyclonal antibody specifically detects HADHA in WB, IF and IP. It exhibits reactivity toward Human.

Quick Overview for HADHA antibody (AA 484-763) (ABIN6141586)

Target: HADHA (Hydroxyacyl-Coenzyme A Dehydrogenase/3-Ketoacyl-Coenzyme A Thiolase/enoyl-Coenzyme A Hydratase (Trifunctional Protein), alpha Subunit (HADHA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HADHA antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details anti-HADHA Antibody

Binding Specificity: AA 484-763

Sequence: IAAVSKRPEK VIGMHYFSPV DKMQLLEIIT TEKTSKDTSA SAVAVGLKQG KVIIVVKDGP GFYTTRCLAP MMSEVIRILQ EGVDPKKLDS LTTSFGFPVG AATLVDEVGV DVAKHVAEDL GKVFGERFGG GNPELLTQMV SKGFLGRKSG KGFYIYQEGV KRKDLNSDMD SILASLKLPP KSEVSSDEDI QFRLVTRFVN EAVMCLQEGI LATPAEGDIG AVFGLGFPPC LGGPFRFVDL YGAQKIVDRL KKYEAAYGKQ FTPCQLLADH ANSPNKKFYQ

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 484-763 of human HADHA (NP_000173.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for HADHA

Target: HADHA (Hydroxyacyl-Coenzyme A Dehydrogenase/3-Ketoacyl-Coenzyme A Thiolase/enoyl-Coenzyme A Hydratase (Trifunctional Protein), alpha Subunit (HADHA))

Alternative Name: HADHA

Background: This gene encodes the alpha subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the alpha subunit catalyzing the 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities. Mutations in this gene result in trifunctional protein deficiency or LCHAD deficiency. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation.,HADHA,ECHA,GBP,HADH,LCEH,LCHAD,MTPA,TP-ALPHA,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Lipid Metabolism,Cardiovascular,Lipids,Fatty Acids,HADHA

Molecular Weight: 28 kDa/83 kDa

Gene ID: 3030

UniProt: P40939

Pathways: Monocarboxylic Acid Catabolic Process