NCALD antibody (C-Term)

Catalog No. ABIN2844186

The Rabbit Polyclonal anti-NCALD antibody is suitable to detect NCALD in samples from Human and Mouse. It has been validated for WB.

Quick Overview for NCALD antibody (C-Term) (ABIN2844186)

Target: NCALD (Neurocalcin delta (NCALD))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCALD antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB22143

Product Details anti-NCALD Antibody

Binding Specificity: AA 147-174, C-Term

Predicted Reactivity: B, Pig, Rat, C, Pr, X

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NCALD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-174 amino acids from the C-terminal region of human NCALD.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for NCALD

Target: NCALD (Neurocalcin delta (NCALD))

Alternative Name: NCALD

Background: NCALD encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels, however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of this gene have been determined, all of which encode the same protein, additional variants may exist but their biological validity has not been determined.

Molecular Weight: 22245

Gene ID: 83988

NCBI Accession: NP_001035714, NP_001035715, NP_001035716, NP_001035717, NP_001035718, NP_001035719, NP_001035720, NP_114430

UniProt: P61601