Presenilin 1 antibody (N-Term)

Catalog No. ABIN285063

This anti-Presenilin 1 antibody is a Goat Polyclonal antibody detecting Presenilin 1 in . Suitable for Human.

Quick Overview for Presenilin 1 antibody (N-Term) (ABIN285063)

Target: Presenilin 1 (PSEN1)

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This Presenilin 1 antibody is un-conjugated

Application: Please inquire

Product Details anti-Presenilin 1 Antibody

Binding Specificity: AA 14-33, N-Term

Immunogen: Presenilin 1 antibody was raised in goat using a synthetic peptide corresponding to amino acid residues 14-33 of the N-terminus of the alzheimer's disease presenilin-1 as the immunogen.

Isotype: IgG

Application Details

Application Notes: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: PBS, pH 7.4, with 0.05 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Target Details for Presenilin 1

Target: Presenilin 1 (PSEN1)

Alternative Name: Presenilin 1

Background: Presenilins are a family of related multi-pass transmembrane proteins that function as a part of the gamma-secretase protease complex. Vertebrates have two presenilin genes, called PSEN1 (located on chromosome 14 in humans) that encodes presenilin 1 (PS-1) and PSEN2 (on chromosome 1 in humans) that codes for presenilin 2 (PS-2).

Pathways: Notch Signaling, EGFR Signaling Pathway, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport