TGFA antibody

Catalog No. ABIN285123

The Sheep Polyclonal anti-TGFA antibody (ABIN285123) specifically detects TGFA in IHC, IP and ELISA. The antibody is reactive with Human samples.

Quick Overview for TGFA antibody (ABIN285123)

Target: TGFA (Transforming Growth Factor, alpha (TGFA))

Reactivity: Human

Host: Sheep

Clonality: Polyclonal

Conjugate: This TGFA antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunoprecipitation (IP), ELISA

Product Details anti-TGFA Antibody

Immunogen: TGF alpha antibody was raised in sheep using mature human recombinant TGF-KLH as the immunogen.

Application Details

Application Notes: ELISA: 1:16,000, IHC: 1:25-1:100, IP: 1:250-1:1,000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: IgG fraction supplied in PBS, pH 7.4, with 0.01 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Target Details for TGFA

Target: TGFA (Transforming Growth Factor, alpha (TGFA))

Alternative Name: TGF alpha

Background: TGF alpha (aa 50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.

Pathways: NF-kappaB Signaling, RTK Signaling, EGFR Signaling Pathway