TNC antibody (C-Term)

Catalog No. ABIN2854287

The Rabbit Polyclonal anti-TNC antibody (ABIN2854287) specifically detects TNC in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for TNC antibody (C-Term) (ABIN2854287)

Target: TNC (Tenascin C (TNC))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNC antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TNC Antibody

Binding Specificity: C-Term

Cross-Reactivity: Dog, Human

Characteristics: Rabbit polyclonal antibody to Tenascin-C (tenascin C)
Tenascin-C antibody [C3], C-term

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human Tenascin C. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for TNC

Target: TNC (Tenascin C (TNC))

Alternative Name: tenascin C

Background: Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6.

Cellular Localization: Secreted , extracellular space , extracellular matrix

Molecular Weight: 241 kDa

Gene ID: 3371

UniProt: P24821

Pathways: Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development