ACRV1 antibody

Catalog No. ABIN2854573

This Rabbit Polyclonal antibody specifically detects ACRV1 in WB. It exhibits reactivity toward Human.

Quick Overview for ACRV1 antibody (ABIN2854573)

Target: ACRV1 (Acrosomal Vesicle Protein 1 (ACRV1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACRV1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ACRV1 Antibody

Cross-Reactivity: Mouse

Characteristics: Rabbit Polyclonal antibody to Acrosomal vesicle protein (acrosomal vesicle protein 1)
Acrosomal vesicle protein antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Acrosomal vesicle protein. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:5000-1:20000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: mouse testis

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for ACRV1

Target: ACRV1 (Acrosomal Vesicle Protein 1 (ACRV1))

Alternative Name: acrosomal vesicle protein 1

Background: This gene encodes a testis-specific, differentiation antigen, acrosomal vesicle protein 1, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the acrosomal membranes and matrix of mature sperm. This gene consists of 4 exons and its alternative splicing generates multiple distinct transcripts, which encode protein isoforms ranging from 81 to 265 amino acids. The longest transcript is the most abundant, comprising 53-72 % of the total acrosomal vesicle protein 1 messages, the second largest transcript comprises 15-32 %, the third and the fourth largest transcripts account for 3.4-8.3 % and 8.7-12.5 %, respectively, and the remaining transcripts combined account for < 1 % of the total acrosomal vesicle protein 1 message. It is suggested that phenomena of cryptic splicing and exon skipping occur within this gene. The acrosomal vesicle protein 1 may be involved in sperm-zona binding or penetration, and it is a potential contraceptive vaccine immunogen for humans.

Cellular Localization: Acrosome

Molecular Weight: 28 kDa

Gene ID: 56

UniProt: P26436