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Endothelin-1 Receptor antibody (C-Term)

EDNRA Reactivity: Rat IHC, IF, IP, IC Host: Sheep Polyclonal unconjugated
Catalog No. ABIN285478
  • Target See all Endothelin-1 Receptor (EDNRA) Antibodies
    Endothelin-1 Receptor (EDNRA) (Endothelin Receptor Type A (EDNRA))
    Binding Specificity
    • 8
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 44
    • 24
    • 20
    • 16
    • 16
    • 15
    • 13
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Rat
    Host
    • 50
    • 3
    • 3
    • 1
    Sheep
    Clonality
    • 55
    • 2
    Polyclonal
    Conjugate
    • 33
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Endothelin-1 Receptor antibody is un-conjugated
    Application
    • 37
    • 17
    • 13
    • 13
    • 8
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunochromatography (IC)
    Specificity
    This peptide sequence is used when generating the antibody and has no significant homology with UPC1 or UPC3. Predicted cross reactivity is based on rat, hamster at 100% and human, pig, bovine, canine at 86%.
    Cross-Reactivity
    Mouse (Murine)
    Purification
    purified
    Immunogen
    Endothelin A receptor antibody was raised in sheep using C-terminal peptide QEQNHNTERSSHK residues 410 - 422 of rat ET(A) Receptor conjugated to KLH as the immunogen.
    Top Product
    Discover our top product EDNRA Primary Antibody
  • Application Notes
    IC: 10-20 µg/mL, IF: 10-20 µg/mL, IHC: 10-20 µg/mL, IP: 20-40 µg/mL
    Optimal conditions should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    Lot specific
    Buffer
    Protein G purified and supplied in PBS, pH 7.5.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Storage
    -20 °C
    Storage Comment
    Aliquot and store at -20 °C.
  • Lampmann, Borger, Konczalla, Gispert, Auburger, Vatter, Güresir: "Experimental Induction of Intracranial Aneurysms in Rats: A New Model Utilizing a Genetic Modification within the EDNRA Gene." in: Brain sciences, Vol. 12, Issue 9, (2022) (PubMed).

  • Target
    Endothelin-1 Receptor (EDNRA) (Endothelin Receptor Type A (EDNRA))
    Alternative Name
    Endothelin A Receptor (EDNRA Products)
    Background
    Endothelins are a family of peptides that are potent vasoconstrictors produced by mammalian vascular endothelial cells. The receptors for endothelins are widely expressed on tissues.
    Pathways
    cAMP Metabolic Process
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