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Endothelin-1 Receptor antibody (AA 132-162)

EDNRA Reactivity: Human WB, IF, FACS, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN452933
  • Target See all Endothelin-1 Receptor (EDNRA) Antibodies
    Endothelin-1 Receptor (EDNRA) (Endothelin Receptor Type A (EDNRA))
    Binding Specificity
    • 10
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 132-162
    Reactivity
    • 41
    • 26
    • 20
    • 16
    • 16
    • 15
    • 13
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Human
    Host
    • 46
    • 3
    • 3
    • 1
    Rabbit
    Clonality
    • 51
    • 2
    Polyclonal
    Conjugate
    • 33
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Endothelin-1 Receptor antibody is un-conjugated
    Application
    • 35
    • 17
    • 13
    • 10
    • 10
    • 5
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects Human Endothelin A receptor at Center. Other species not tested.
    Purification
    Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
    Immunogen
    KLH conjugated synthetic peptide selected between aa 132-162 amino acids from the Center region of Human EDNRA
    Top Product
    Discover our top product EDNRA Primary Antibody
  • Application Notes
    Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000. Flow cytometry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS, 0.09 % (W/V) Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    Endothelin-1 Receptor (EDNRA) (Endothelin Receptor Type A (EDNRA))
    Alternative Name
    Endothelin A Receptor (EDNRA Products)
    Synonyms
    ET-A antibody, ETA antibody, ETA-R antibody, ETAR antibody, ETRA antibody, hET-AR antibody, ET-AR antibody, Endor antibody, Eta antibody, RGD1559432 antibody, ETa antibody, Gpcr10 antibody, ednr-a antibody, ednra antibody, wu:fb75g12 antibody, ednraa antibody, eta antibody, etar antibody, etra antibody, zgc:85942 antibody, endothelin receptor type A antibody, endothelin receptor type Aa antibody, endothelin receptor type A L homeolog antibody, endothelin receptor type Ab antibody, EDNRA antibody, Ednra antibody, ednraa antibody, ednra.L antibody, ednra antibody, ednrab antibody
    Background
    EDNRA is a receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Function: Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3 Cellular Location: Cell membrane, Multi-pass membrane protein. Tissue Location: Isoform 1, isoform 3 and isoform 4 are expressed in a variety of tissues, with highest levels in the aorta and cerebellum, followed by lung, atrium and cerebral cortex, lower levels in the placenta, kidney, adrenal gland, duodenum, colon, ventricle and liver but no expression in umbilical vein endothelial cells. Within the placenta, isoform 1, isoform 2, isoform 3 and isoform 4 are expressed in the villi and stem villi vessels.Synonyms: EDNRA, ET-A, ETA, ETA-R, ETRA, Endothelin-1 receptor, endothelin receptor type A, hET-AR
    Molecular Weight
    48722 Da
    Gene ID
    1909
    NCBI Accession
    NP_001948
    UniProt
    P25101
    Pathways
    cAMP Metabolic Process
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