Lipase A antibody (Center)

Catalog No. ABIN2854960

This Rabbit Polyclonal antibody specifically detects Lipase A in WB. It exhibits reactivity toward Human and Mouseand has been mentioned in 1 publication.

Quick Overview for Lipase A antibody (Center) (ABIN2854960)

Target: Lipase A (LIPA) (Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Lipase A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Lipase A Antibody

Binding Specificity: Center

Cross-Reactivity: Pig (Porcine)

Cross-Reactivity (Details): Pig (84 %)

Characteristics: Rabbit Polyclonal antibody to LAL (lipase A, lysosomal acid, cholesterol esterase)
LAL antibody [N3C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human LAL. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*

Comment:

Positive Control: A549 , H1299 , mouse liver

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

References for anti-Lipase A antibody (ABIN2854960)

Rivera-Serrano, González-López, Das, Lemon: "Cellular entry and uncoating of naked and quasi-enveloped human hepatoviruses." in: eLife, Vol. 8, (2019) (PubMed).

Target Details for Lipase A

Target: Lipase A (LIPA) (Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA))

Alternative Name: LAL

Background: This gene encodes lipase A, the lysosomal acid lipase (also known as cholesterol ester hydrolase). This enzyme functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides. Mutations in this gene can result in Wolman disease and cholesteryl ester storage disease. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Cellular Localization: Lysosome

Molecular Weight: 45 kDa

Gene ID: 3988