RGS6 antibody (C-Term)
Quick Overview for RGS6 antibody (C-Term) (ABIN285498)
Target
See all RGS6 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Specificity
- This monoclonal antibody crossreacts to THC and metabolite. There is no reactivityagainst Opiates, Cocaine Metabolites, Amphetamine or Phencylidine.
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Cross-Reactivity (Details)
- This antibody recognizes human GAP and may crossreact with other species.
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Purification
- Protein G affinity chromatography
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Immunogen
- GAP antibody was raised in sheep using human GTPase Activating Protein (C-terminal peptide)-KLH as the immunogen.
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Application Notes
- Optimal conditions should be determined byt he investigator.
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Restrictions
- For Research Use only
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Concentration
- Lot specific
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Buffer
- Protein G purified and supplied in 150 mM PBS buffer, pH 7.3.
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Handling Advice
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Storage
- -20 °C
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Storage Comment
- Aliquot and store at -20 °C.
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- RGS6 (Regulator of G-Protein Signaling 6 (RGS6))
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Alternative Name
- GAP
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Background
- GTPase-Activating Proteins, or GAPs, or GTPase-Accelerating Proteins are a family of regulatory proteins whose members can bind to activated G proteins and stimulate their GTPase activity, with the result of terminating the signaling event. G proteins are switched from the active, GTP-bound form to the inactive, GDP-bound form by hydrolysis of the GTP through intrinsic GTPase-activity.
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Pathways
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
Target
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