RGS6 antibody (C-Term)

Catalog No. ABIN285498

The Sheep Polyclonal anti-RGS6 antibody (ABIN285498) specifically detects RGS6 in WB and IP. The antibody is reactive with Human samples.

Quick Overview for RGS6 antibody (C-Term) (ABIN285498)

Target: RGS6 (Regulator of G-Protein Signaling 6 (RGS6))

Reactivity: Human

Host: Sheep

Clonality: Polyclonal

Conjugate: This RGS6 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-RGS6 Antibody

Binding Specificity: C-Term

Specificity: This monoclonal antibody crossreacts to THC and metabolite. There is no reactivityagainst Opiates, Cocaine Metabolites, Amphetamine or Phencylidine.

Cross-Reactivity (Details): This antibody recognizes human GAP and may crossreact with other species.

Purification: Protein G affinity chromatography

Immunogen: GAP antibody was raised in sheep using human GTPase Activating Protein (C-terminal peptide)-KLH as the immunogen.

Application Details

Application Notes: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Protein G purified and supplied in 150 mM PBS buffer, pH 7.3.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 °C.

Target Details for RGS6

Target: RGS6 (Regulator of G-Protein Signaling 6 (RGS6))

Alternative Name: GAP

Background: GTPase-Activating Proteins, or GAPs, or GTPase-Accelerating Proteins are a family of regulatory proteins whose members can bind to activated G proteins and stimulate their GTPase activity, with the result of terminating the signaling event. G proteins are switched from the active, GTP-bound form to the inactive, GDP-bound form by hydrolysis of the GTP through intrinsic GTPase-activity.

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling