ADCY2 antibody

Catalog No. ABIN2855022

This anti-ADCY2 antibody is a Rabbit Polyclonal antibody detecting ADCY2 in WB and IHC (p). Suitable for Human.

Quick Overview for ADCY2 antibody (ABIN2855022)

Target: ADCY2 (Adenylate Cyclase 2 (Brain) (ADCY2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADCY2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ADCY2 Antibody

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to Adenylate cyclase 2 (adenylate cyclase 2 (brain))
Adenylate cyclase 2 antibody [N3C1], Internal

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Adenylate cyclase 2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: IMR32

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.33 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for ADCY2

Target: ADCY2 (Adenylate Cyclase 2 (Brain) (ADCY2))

Alternative Name: adenylate cyclase 2

Background: This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This enzyme is insensitive to Ca(2+)/calmodulin, and is stimulated by the G protein beta and gamma subunit complex.

Cellular Localization: Membrane

Molecular Weight: 124 kDa

Gene ID: 108

UniProt: Q08462

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma