GDI1 antibody

Catalog No. ABIN2855146

This Rabbit Polyclonal antibody specifically detects GDI1 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for GDI1 antibody (ABIN2855146)

Target: GDI1 (GDP Dissociation Inhibitor 1 (GDI1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GDI1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-GDI1 Antibody

Cross-Reactivity: Human, Mouse

Characteristics: Rabbit Polyclonal antibody to GDI1 (GDP dissociation inhibitor 1)
GDI1 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human GDI1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HepG2 , NIH-3T3

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.15 mg/mL

Buffer: 1XPBS ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for GDI1

Target: GDI1 (GDP Dissociation Inhibitor 1 (GDI1))

Alternative Name: GDP dissociation inhibitor 1

Background: GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation.

Cellular Localization: Cytoplasm

Molecular Weight: 51 kDa

Gene ID: 2664

UniProt: P31150