RUVBL2 antibody (C-Term)

Catalog No. ABIN2855264

The Rabbit Polyclonal anti-RUVBL2 antibody has been validated for WB and IHC (p). It is suitable to detect RUVBL2 in samples from Human.

Quick Overview for RUVBL2 antibody (C-Term) (ABIN2855264)

Target: RUVBL2 (RuvB-Like 2 (E. Coli) (RUVBL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RUVBL2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-RUVBL2 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Rhesus Monkey

Cross-Reactivity (Details): Rhesus Monkey (100 %)

Characteristics: Rabbit Polyclonal antibody to RUVBL2 (RuvB-like 2 (E. coli))
RUVBL2 antibody [C1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human RUVBL2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:1000-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:1000-1:10000*

Comment:

Positive Control: 293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.94 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for RUVBL2

Target: RUVBL2 (RuvB-Like 2 (E. Coli) (RUVBL2))

Alternative Name: RUVBL2

Background: This gene encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities. This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation.

Cellular Localization: Nucleus matrix , Nucleus , nucleoplasm , Cytoplasm , Membrane

Molecular Weight: 51 kDa

Gene ID: 10856

Pathways: Telomere Maintenance