ATP2A3 antibody (N-Term)

Catalog No. ABIN2855377

This Rabbit Polyclonal antibody specifically detects ATP2A3 in WB and IHC (p). It exhibits reactivity toward Human and Mouse.

Quick Overview for ATP2A3 antibody (N-Term) (ABIN2855377)

Target: ATP2A3 (ATPase, Ca++ Transporting, Ubiquitous (ATP2A3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP2A3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ATP2A3 Antibody

Binding Specificity: N-Term

Cross-Reactivity: Chicken, Rat (Rattus), Xenopus laevis, Cow (Bovine), Xenopus tropicalis

Cross-Reactivity (Details): Chicken (88 %), Rat (99 %), Xenopus laevis (92 %), Bovine (98 %), Xenopus tropicalis (91 %)

Characteristics: Rabbit Polyclonal antibody to SERCA3 (ATPase, Ca++ transporting, ubiquitous)
SERCA3 antibody [N1N2], N-term

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human SERCA3. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:1000-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:1000-1:10000*

Comment:

Positive Control: Jurkat , Raji , K562 , BCL-1

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS, 1 % BSA, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for ATP2A3

Target: ATP2A3 (ATPase, Ca++ Transporting, Ubiquitous (ATP2A3))

Alternative Name: SERCA3

Background: This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in calcium sequestration associated with muscular excitation and contraction. Alternative splicing results in multiple transcript variants encoding different isoforms.

Cellular Localization: Nucleus membrane , Endoplasmic reticulum membrane , Sarcoplasmic reticulum membrane

Molecular Weight: 114 kDa

Gene ID: 489

Pathways: Myometrial Relaxation and Contraction, Ribonucleoside Biosynthetic Process