PRPS1 antibody (N-Term)

Catalog No. ABIN2855446

This Rabbit Polyclonal antibody specifically detects PRPS1 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for PRPS1 antibody (N-Term) (ABIN2855446)

Target: PRPS1 (phosphoribosyl Pyrophosphate Synthetase 1 (PRPS1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRPS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PRPS1 Antibody

Binding Specificity: N-Term

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Rabbit Polyclonal antibody to PRPS1 (phosphoribosyl pyrophosphate synthetase 1)
PRPS1 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human PRPS1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-1:10000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Mouse kidney , Rat liver , 293T

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.58 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for PRPS1

Target: PRPS1 (phosphoribosyl Pyrophosphate Synthetase 1 (PRPS1))

Alternative Name: phosphoribosyl pyrophosphate synthetase 1

Background: This gene encodes an enzyme that catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for purine metabolism and nucleotide biosynthesis. Defects in this gene are a cause of phosphoribosylpyrophosphate synthetase superactivity, Charcot-Marie-Tooth disease X-linked recessive type 5 and Arts Syndrome.

Molecular Weight: 35 kDa

Gene ID: 5631

UniProt: P60891

Pathways: Ribonucleoside Biosynthetic Process