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PRPS1 antibody (N-Term)

PRPS1 Reactivity: Human, Mouse WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN359137
  • Target See all PRPS1 Antibodies
    PRPS1 (phosphoribosyl Pyrophosphate Synthetase 1 (PRPS1))
    Binding Specificity
    • 2
    • 2
    • 1
    N-Term
    Reactivity
    • 8
    • 3
    • 2
    Human, Mouse
    Host
    • 6
    • 2
    Rabbit
    Clonality
    • 7
    • 1
    Polyclonal
    Conjugate
    • 8
    This PRPS1 antibody is un-conjugated
    Application
    • 8
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody reacts to PRPS1/PRPS2/PRPS3.
    Purification
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human PRPS1/2/3.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PRPS1 Primary Antibody
  • Application Notes
    ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    PRPS1 (phosphoribosyl Pyrophosphate Synthetase 1 (PRPS1))
    Alternative Name
    PRPS1 (PRPS1 Products)
    Synonyms
    ARTS antibody, CMTX5 antibody, DFN2 antibody, DFNX1 antibody, PPRibP antibody, PRS-I antibody, PRSI antibody, 2310010D17Rik antibody, C76571 antibody, C76678 antibody, Prps-1 antibody, cb96 antibody, prps1 antibody, wu:fa18f03 antibody, wu:fb33h12 antibody, wu:fd26g08 antibody, zgc:55299 antibody, zgc:76932 antibody, arts antibody, cmtx5 antibody, ppribp antibody, prsi antibody, fc64g03 antibody, im:6909503 antibody, wu:fc64g03 antibody, zgc:153331 antibody, phosphoribosyl pyrophosphate synthetase 1 antibody, phosphoribosyl pyrophosphate synthetase 1A antibody, phosphoribosyl pyrophosphate synthetase 1 L homeolog antibody, phosphoribosyl pyrophosphate synthetase 1B antibody, PRPS1 antibody, Prps1 antibody, prps1a antibody, prps1.L antibody, prps1b antibody
    Background
    Phosphoribosylpyrophosphate synthetase (PRPS, EC 2.7.6.1) catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for the de novo and salvage pathways of purine, pyrimidine, and pyridine biosynthesis. By PCR of human lymphoblast mRNA using primers based on the cDNA sequence of rat PRS I (Prps1), Roessler et al. (1990) isolated a partial human PRPS1 cDNA. They used this partial cDNA to screen lymphoblast cDNA libraries and isolated additional cDNAs corresponding to the entire PRPS1 coding region. The deduced PRPS1 protein has 318 amino acids.Synonyms: PPRibP, PRS-I, Phosphoribosyl pyrophosphate synthetase I, Ribose-phosphate pyrophosphokinase I
    Gene ID
    5631, 9606
    UniProt
    P60891
    Pathways
    Ribonucleoside Biosynthetic Process
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