PRPS1 antibody (AA 1-318)

Catalog No. ABIN7596089

The Mouse Monoclonal anti-PRPS1 antibody (Clone AT1E11) (ABIN7596089) specifically detects PRPS1 in WB, ELISA, IF and ICC. The antibody is reactive with Human samples.

Quick Overview for PRPS1 antibody (AA 1-318) (ABIN7596089)

Target: PRPS1 (phosphoribosyl Pyrophosphate Synthetase 1 (PRPS1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PRPS1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: AT1E11

Product Details anti-PRPS1 Antibody

Binding Specificity: AA 1-318

Purpose: Human PRPS1 antibody

Purification: Purified

Immunogen: Recombinant human PRPS1 (1-318aa) purified from E. coli

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing cycles

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for PRPS1

Target: PRPS1 (phosphoribosyl Pyrophosphate Synthetase 1 (PRPS1))

Alternative Name: PRPS1

Background: PRPS1 is an enzyme that catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for purine metabolism and nucleotide biosynthesis. A mutation in PRPS1 may result in PRPS superactivity, a disease characterized by gout and the overproductionof purine nucleotides, uric acid and PRPP. PRPS1 mutations can also lead to a reduction in PRPS1 activity resulting in ARTS syndrome or CMTX5 (Charcot-Marie-Tooth disease X-linked recessive type 5).

NCBI Accession: NP_002755

Pathways: Ribonucleoside Biosynthetic Process