CDKL3 antibody

Catalog No. ABIN2855643

This anti-CDKL3 antibody is a Rabbit Polyclonal antibody detecting CDKL3 in WB. Suitable for Human.

Quick Overview for CDKL3 antibody (ABIN2855643)

Target: CDKL3 (Cyclin-Dependent Kinase-Like 3 (CDKL3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDKL3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CDKL3 Antibody

Cross-Reactivity: Human

Characteristics: Rabbit Polyclonal antibody to NKIAMRE (cyclin-dependent kinase-like 3)
NKIAMRE antibody [N1C1]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human NKIAMRE. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: NT2D1 , IMR32

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.03 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for CDKL3

Target: CDKL3 (Cyclin-Dependent Kinase-Like 3 (CDKL3))

Alternative Name: cyclin dependent kinase like 3

Background: The protein encoded by this gene is a member of cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This gene was identified as a gene absent in leukemic patients with chromosome 5q deletion. This loss may be an important determinant of dysmyelopoiesis. Alternative splicing results in multiple transcript variants encoding different isoforms.

Cellular Localization: Cytoplasm

Molecular Weight: 68 kDa

Gene ID: 51265

UniProt: Q8IVW4

Pathways: Cell Division Cycle