CDKL3 antibody (AA 260-340)

Catalog No. ABIN7222996

The Rabbit Polyclonal anti-CDKL3 antibody is suitable to detect CDKL3 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IHC and IF.

Quick Overview for CDKL3 antibody (AA 260-340) (ABIN7222996)

Target: CDKL3 (Cyclin-Dependent Kinase-Like 3 (CDKL3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDKL3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-CDKL3 Antibody

Binding Specificity: AA 260-340

Purpose: Rabbit Anti-NKIAMRE Polyclonal Antibody

Specificity: NKIAMRE Polyclonal Antibody detects endogenous levels of NKIAMRE protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human NKIAMRE at AA range: 260-340

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CDKL3

Target: CDKL3 (Cyclin-Dependent Kinase-Like 3 (CDKL3))

Alternative Name: NKIAMRE

Background: CDKL3, NKIAMRE, Cyclin-dependent kinase-like 3, Serine/threonine-protein kinase NKIAMREThe protein encoded by CDKL3 (cyclin dependent kinase like 3) is a member of cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. CDKL3 was identified as a gene absent in leukemic patients with chromosome 5q deletion. This loss may be an important determinant of dysmyelopoiesis. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight: 67kD

Gene ID: 51265

UniProt: Q8IVW4

Pathways: Cell Division Cycle