Thimet Oligopeptidase 1 antibody
Quick Overview for Thimet Oligopeptidase 1 antibody (ABIN2855746)
Target
See all Thimet Oligopeptidase 1 (THOP1) AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Cross-Reactivity
- Human
-
Characteristics
-
Rabbit polyclonal antibody to Thimet Oligopeptidase (thimet oligopeptidase 1)
Thimet Oligopeptidase antibody [N2C2], Internal -
Purification
- Purified by antigen-affinity chromatography.
-
Immunogen
- Recombinant protein encompassing a sequence within the center region of human Thimet Oligopeptidase. The exact sequence is proprietary.
-
Isotype
- IgG
-
-
-
-
Application Notes
- WB: 1:1000-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
-
Comment
-
Positive Control: A431
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.93 mg/mL
-
Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
-
Preservative
- Thimerosal (Merthiolate)
-
Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- 4 °C,-20 °C
-
Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
- Thimet Oligopeptidase 1 (THOP1)
-
Alternative Name
- thimet oligopeptidase 1
-
Background
-
Involved in the metabolism of neuropeptides under 20 amino acid residues long. Involved in cytoplasmic peptide degradation. Able to degrade the beta-amyloid precursor protein and generate amyloidogenic fragments.
Cellular Localization: Cytoplasm -
Molecular Weight
- 79 kDa
-
Gene ID
- 7064
-
UniProt
- P52888
Target
-