ME1 antibody
Quick Overview for ME1 antibody (ABIN2855777)
Target
See all ME1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Grade
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
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Rabbit Polyclonal antibody to ME1 (malic enzyme 1, NADP(+)-dependent, cytosolic)
ME1 antibody -
Purification
- Purified by antigen-affinity chromatography.
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Immunogen
- Recombinant protein encompassing a sequence within the center region of human ME1. The exact sequence is proprietary.
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Isotype
- IgG
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anti-Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1) (AA 1-572) antibody
ME1 Reactivity: Human WB, ELISA, IHC (p) Host: Mouse Monoclonal 3H5 unconjugated
anti-Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1) (AA 161-519) antibodyME1 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1) (AA 1-572) antibodyME1 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1) (AA 1-572) antibodyME1 Reactivity: Human WB Host: Mouse Monoclonal 2A2 unconjugated
anti-Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1) (AA 1-572) antibodyME1 Reactivity: Human, Mouse, Rat WB, IHC Host: Mouse Monoclonal 5E5F7 unconjugated
anti-Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1) (AA 37-70) antibodyME1 Reactivity: Human WB Host: Rabbit Polyclonal RB55906 unconjugated
anti-Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1) (AA 36-85) antibodyME1 Reactivity: Human, Dog, Pig WB Host: Rabbit Polyclonal unconjugated
anti-Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1) (AA 1-300) antibodyME1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1) (C-Term) antibodyME1 Reactivity: Human, Mouse, Rat WB, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1) (N-Term) antibodyME1 Reactivity: Human, Mouse, Rat, Dog, Rabbit, Horse, Pig, Sheep, Cow WB, IHC Host: Rabbit Polyclonal unconjugated
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Application Notes
- WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Comment
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Positive Control: PC-12 , NIH-3T3 , JC , BCL-1
Validation: KO/KD
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.94 mg/mL
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Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- ME1 (Malic Enzyme 1, NADP(+)-Dependent, Cytosolic (ME1))
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Alternative Name
- malic enzyme 1
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Background
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This gene encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet.
Cellular Localization: Cytoplasm -
Molecular Weight
- 64 kDa
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Gene ID
- 4199
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UniProt
- P48163
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Pathways
- Regulation of Lipid Metabolism by PPARalpha
Target
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