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AICDA antibody (N-Term)

AICDA Reactivity: Human WB, IHC (p), ICC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2855890
  • Target See all AICDA Antibodies
    AICDA (Activation-Induced Cytidine Deaminase (AICDA))
    Binding Specificity
    • 15
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 41
    • 14
    • 6
    • 2
    • 1
    Human
    Host
    • 35
    • 3
    • 2
    • 1
    Rabbit
    Clonality
    • 37
    • 4
    Polyclonal
    Conjugate
    • 24
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AICDA antibody is un-conjugated
    Application
    • 36
    • 19
    • 13
    • 13
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Cross-Reactivity
    Human, Mouse
    Characteristics
    Rabbit Polyclonal antibody to AICDA (activation-induced cytidine deaminase)
    AICDA antibody [N1N2], N-term
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human AICDA. The exact sequence is proprietary.
    Isotype
    IgG
  • Application Notes
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: 293T

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    1XPBS ( pH 7), 40 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    AICDA (Activation-Induced Cytidine Deaminase (AICDA))
    Alternative Name
    activation induced cytidine deaminase (AICDA Products)
    Synonyms
    AID antibody, ARP2 antibody, CDA2 antibody, HIGM2 antibody, Aid antibody, Arp2 antibody, aid antibody, AICDA antibody, arp2 antibody, cda2 antibody, higm2 antibody, xlaid antibody, activation induced cytidine deaminase antibody, activation-induced cytidine deaminase antibody, activation-induced cytidine deaminase L homeolog antibody, AICDA antibody, Aicda antibody, aicda antibody, aicda.L antibody
    Background
    This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2).

    Molecular Weight
    24 kDa
    Gene ID
    57379
    UniProt
    Q9GZX7
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Production of Molecular Mediator of Immune Response
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