MZB1 antibody

Catalog No. ABIN2856434

The Rabbit Polyclonal anti-MZB1 antibody is suitable to detect MZB1 in samples from Human. It has been validated for WB, IF, ICC, IHC (p) and IHC (fro).

Quick Overview for MZB1 antibody (ABIN2856434)

Target: MZB1 (Marginal Zone B and B1 Cell-Specific Protein (MZB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MZB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-MZB1 Antibody

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Rabbit polyclonal antibody to PACAP
PACAP antibody [N1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human PACAP. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Molt-4 , Raji , mouse spleen

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.02 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for MZB1

Target: MZB1 (Marginal Zone B and B1 Cell-Specific Protein (MZB1))

Alternative Name: marginal zone B and B1 cell specific protein

Background: Associates with immunoglobulin M (IgM) heavy and light chains and promotes IgM assembly and secretion. May exert its effect by acting as a molecular chaperone or as an oxidoreductase as it displays a low level of oxidoreductase activity (By similarity). Isoform 2 may be involved in regulation of apoptosis.

Cellular Localization: Secreted (Potential) , Cytoplasm

Molecular Weight: 21 kDa

Gene ID: 51237

UniProt: Q8WU39

Pathways: Production of Molecular Mediator of Immune Response