B3GNT3 antibody

Catalog No. ABIN2856643

This Rabbit Polyclonal antibody specifically detects B3GNT3 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for B3GNT3 antibody (ABIN2856643)

Target: B3GNT3 (UDP-GlcNAc:betaGal beta-1,3-N-Acetylglucosaminyltransferase 3 (B3GNT3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This B3GNT3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-B3GNT3 Antibody

Cross-Reactivity: Human, Mouse

Characteristics: Rabbit Polyclonal antibody to B3GNT3 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3)
B3GNT3 antibody

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human B3GNT3. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Mouse stomach , 293T

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for B3GNT3

Target: B3GNT3 (UDP-GlcNAc:betaGal beta-1,3-N-Acetylglucosaminyltransferase 3 (B3GNT3))

Alternative Name: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3

Background: This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein and contains a signal anchor that is not cleaved. It prefers the substrates of lacto-N-tetraose and lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains and the biosynthesis of the backbone structure of dimeric sialyl Lewis a. It plays dominant roles in L-selectin ligand biosynthesis, lymphocyte homing and lymphocyte trafficking.

Cellular Localization: Golgi apparatus membrane

Molecular Weight: 43 kDa

Gene ID: 10331

UniProt: Q9Y2A9

Pathways: Glycosaminoglycan Metabolic Process