CCR7 antibody (AA 2-22)

Catalog No. ABIN285675

Product Details anti-CCR7 Antibody

Target: CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

Binding Specificity: AA 2-22

Reactivity: Mouse

Host: Goat

Clonality: Polyclonal

Conjugate: This CCR7 antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunochromatography (IC)

Cross-Reactivity: Human

Cross-Reactivity (Details): Peptide sequence is <50 % identical to other mouse chemokine receptors inthis region and crossreacts with human CCR7

Immunogen: CCR7 antibody was raised in goat using a synthetic peptide DPGKPRKNVLVVALLVIFQVC corresponding to amino acid residues 2-22 of mouse CCR7 as the immunogen.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:100,000, FC: 1:10, IC: 1:250, IHC: 1:250, WB: 1:1,000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: 10 mM KHPO4, pH 7.2, with 140 M NaCl, 1 mg/mL BSA and 0.1 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: -20 °C/-80 °C

Storage Comment: Aliquot and store at -20 °C for short term storage, -70 °C for long-term storage.

Target Details for CCR7

Target: CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

Alternative Name: CCR7 (CCR7 Products)

Synonyms: zgc:165629 antibody, ccr7-a antibody, CD197 antibody, Cdw197 antibody, Cmkbr7 antibody, EBI1 antibody, Ebi1h antibody, BLR2 antibody, CDw197 antibody, CMKBR7 antibody, chemokine (C-C motif) receptor 7 antibody, C-C motif chemokine receptor 7 antibody, C-C motif chemokine receptor 7 L homeolog antibody, ccr7 antibody, CCR7 antibody, ccr7.L antibody, Ccr7 antibody

Background: C-C chemokine receptor type 7 is a protein that in humans is encoded by the CCR7 gene. CCR7 has also recently been designated CD197 (cluster of differentiation 197). The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes.

Pathways: Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process