CYP1A2 antibody

Catalog No. ABIN285734

The Rabbit Polyclonal anti-CYP1A2 antibody has been validated for WB and IHC. It is suitable to detect CYP1A2 in samples from Human and Rat.

Quick Overview for CYP1A2 antibody (ABIN285734)

Target: CYP1A2 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP1A2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CYP1A2 Antibody

Cross-Reactivity (Details): Reacts with Cytochrome P450 Enzyme CYP1A2 in hepatic microsomal fractions ofhuman and rat. Recognises a 54 kDa protein by Western Blot. No crossreactivity with other cytochrome P450 enzymes.

Immunogen: CYP1 A2 antibody was raised in rabbit using a synthetic peptide as the immunogen.

Application Details

Application Notes: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Neat serum with no preservatives.

Preservative: Without preservative

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 °C.

Target Details for CYP1A2

Target: CYP1A2 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2))

Alternative Name: CYP1A2

Background: The cytochrome P450 superfamily (officially abbreviated as CYP) is a large and diverse group of enzymes. The function of most CYP enzymes is to catalyze the oxidation of organic substances. The substrates of CYP enzymes include metabolic intermediates such as lipids and steroidal hormones, as well as xenobiotic substances such as drugs and other toxic chemicals. Cytochrome P450 1A2 (abbreviated CYP1A2), is involved in the metabolism of xenobiotics in the body. In humans, the CYP1A2 enzyme is encoded by the CYP1A2 gene. Expression of CYP1A2 appears to be induced by various dietary constituents.