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Perforin 1 antibody

PRF1 Reactivity: Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN285909
  • Target See all Perforin 1 (PRF1) Antibodies
    Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))
    Reactivity
    • 80
    • 26
    • 10
    • 7
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    Rat
    Host
    • 57
    • 41
    • 4
    Rabbit
    Clonality
    • 58
    • 44
    Polyclonal
    Conjugate
    • 58
    • 13
    • 11
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Perforin 1 antibody is un-conjugated
    Application
    • 50
    • 40
    • 30
    • 20
    • 15
    • 10
    • 7
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Cross-Reactivity
    Mouse (Murine), Rat (Rattus)
    Cross-Reactivity (Details)
    Reacts with both rat and mouse perforin. Cross-reactivity to perforin of other species has not been tested.
    Purification
    purified
    Immunogen
    Perforin antibody was raised in rabbit using E. coli-expressed rat perforin as the immunogen.
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    Discover our top product PRF1 Primary Antibody
  • Application Notes
    WB: 1:1,000
    Optimal conditions should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitue in distilled water.
    Concentration
    Lot specific
    Buffer
    Supplied as a lyophilized Potein A purified rabbit IgG with 0.1 % NaN3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
  • Target
    Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))
    Alternative Name
    Perforin (PRF1 Products)
    Synonyms
    FLH2 antibody, HPLH2 antibody, P1 antibody, PFN1 antibody, PFP antibody, PRF1 antibody, Pfn antibody, Pfp antibody, Prf-1 antibody, Cyta antibody, RATCYTA antibody, LOC443187 antibody, perforin antibody, prf1 antibody, cytolysin antibody, perforin-1 antibody, perforin-1-like antibody, perforin 1 antibody, perforin 1 (pore forming protein) antibody, perforin antibody, perforin 1 L homeolog antibody, PRF1 antibody, Prf1 antibody, LOC443187 antibody, prf1 antibody, prf1.L antibody
    Background
    Perforin-1 is a protein that in humans is encoded by the PRF1 gene. Perforin is a cytolytic protein found in the granules of CD8 T-cells and NK cells. Upon degranulation, perforin inserts itself into the target cell's plasma membrane, forming a pore. The lytic membrane-inserting part of perforin is the MACPF domain. This region shares homology with cholesterol-dependent cytolysins from Gram-positive bacteria.
    Pathways
    Apoptosis, Caspase Cascade in Apoptosis
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