Caspase 1 antibody (Cleaved-Asp210)

Catalog No. ABIN2891163

This anti-Caspase 1 antibody is a Rabbit Polyclonal antibody detecting Caspase 1 in IHC and ELISA. Suitable for Human.

Quick Overview for Caspase 1 antibody (Cleaved-Asp210) (ABIN2891163)

Target: Caspase 1 (CASP1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caspase 1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-Caspase 1 Antibody

Binding Specificity: AA 192-241, Cleaved-Asp210

Specificity: IL-1 beta (Cleaved-Asp210) Antibody detects endogenous levels of fragment of activated IL-1 beta protein resulting from cleavage adjacent to Asp210.

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide from human CASP1 (aa192-241).

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: IHC (1:50 - 1:100), Peptide-ELISA (1:20000)

Not recommended for: IHC-P

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS (without Mg2+, Ca2+),  pH 7.4, 150 mM sodium chloride, 0.02 % sodium azide, 50 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for up to 1 year.

Expiry Date: 12 months

Target Details for Caspase 1

Target: Caspase 1 (CASP1)

Alternative Name: CASP1 / Caspase 1

Background: Name/Gene ID: CASP1
Subfamily: Cysteine C14
Family: Protease

Synonyms: CASP1, Caspase-1, CASP-1, CASP1 nirs variant 1, Caspase 1, ICE, ICE-like protease, IL-1 beta-converting enzyme, IL-1BC, IL1BC, IL1BCE, p45, IL1B-convertase, Interleukin-1 beta convertase

Gene ID: 834

UniProt: P29466

Pathways: Apoptosis, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome