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Mannose Receptor antibody

MR Reactivity: Human IHC, IHC (fro) Host: Mouse Monoclonal 7-450 unconjugated
Catalog No. ABIN291690
  • Target See all Mannose Receptor (MR) Antibodies
    Mannose Receptor (MR)
    Reactivity
    • 30
    • 23
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    Human
    Host
    • 23
    • 9
    • 8
    Mouse
    Clonality
    • 25
    • 15
    Monoclonal
    Conjugate
    • 15
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Mannose Receptor antibody is un-conjugated
    Application
    • 20
    • 18
    • 9
    • 9
    • 7
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificity
    Specific for human CD206, otherwise known as macrophage mannose receptor (MMR), a transmembrane protein and member of the multilectin family of pattern recognition receptors (PRRs), which mediates phagocytosis and endocytosis, and is modulated by a range of factors including cytokines, immunoglobulin receptors and pathogens. CD206 has two extracellular lectin binding sites: the cysteine-rich domain binds to sulphated sugars of glycoproteins such as thyroid stimulating hormone, whilst the recognition of mannose and fucose occurs through carbohydrate recognition domains (CRDs). The widespread distribution and recognition of a wide range of antigens by macrophages, plays a key role in both innate and adaptive immunity, with CD206 able to bind to both gram-negative and gram-positive bacteria, mycobacterium, yeasts, fungi and parasites.
    Purification
    Affinity purified
    Immunogen
    Monocyte-derived dendritic cells.

    Type of Immunogen: Cells
    Clone
    7-450
    Isotype
    IgG2a
    Top Product
    Discover our top product MR Primary Antibody
  • Application Notes
    Approved: IHC, IHC-Fr (1:50 - 1:500)
    Comment

    Target Species of Antibody: Human

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    PBS,  pH 7.4, 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Short term: -20°C
    Long term: -20°C.
  • Target
    Mannose Receptor (MR)
    Alternative Name
    Mannose Receptor / CD206 (MR Products)
    Synonyms
    CD206 antibody, CLEC13D antibody, CLEC13DL antibody, MMR antibody, MRC1L1 antibody, bA541I19.1 antibody, AW259686 antibody, MR antibody, mannose receptor C-type 1 antibody, mannose receptor, C type 1 antibody, MRC1 antibody, Mrc1 antibody
    Background
    Name/Gene ID: MRC1

    Synonyms: MRC1, BA541I19.1, CLEC13D, CD206, CD206 antigen, Macrophage mannose receptor 1, Mannose Receptor, Macrophage mannose receptor, MMR, Mannose receptor, C type 1, MRC1L1, CLEC13DL
    Gene ID
    4360
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