Mannose Receptor antibody

Catalog No. ABIN7074550

Product Details anti-Mannose Receptor Antibody

Target: Mannose Receptor (MR)

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Mannose Receptor antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Mannose Receptor

Application Details

Application Notes: IHC/IF (M) 1:400-1:800

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for Mannose Receptor

Target: Mannose Receptor (MR)

Alternative Name: Mannose Receptor (MR Products)

Synonyms: CD206 antibody, CLEC13D antibody, CLEC13DL antibody, MMR antibody, MRC1L1 antibody, bA541I19.1 antibody, AW259686 antibody, MR antibody, mannose receptor C-type 1 antibody, mannose receptor, C type 1 antibody, MRC1 antibody, Mrc1 antibody

Background: CD206, also named as MMR, CLEC13D and MRC1, is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. CD206 has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. CD206 is a 170 kDa transmembrane glycoprotein which contains 5 domains: an amino-terminal cysteine-rich region, a fibronectin type II repeat, a series of eight tandem lectin-like carbohydrate recognition domains (responsible for the recognition of mannose and fucose), a transmembrane domain, and an intracellular carboxy-terminal tail.

Gene ID: 17533

UniProt: Q61830