MUSK antibody (Extracellular Domain)
Quick Overview for MUSK antibody (Extracellular Domain) (ABIN293524)
Target
See all MUSK AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Extracellular Domain
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Specificity
- Selected for its ability to recognize human MuSK in direct ELISAs and Western Blots. In these formats, this antibody shows ~60 % cross-reactivity with rrMuSK.
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Purification
- Affinity purified
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Immunogen
- NS0-derived rhMuSK extracellular domain.
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Isotype
- IgG
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Application Notes
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Approved: ELISA, WB
Usage: Western Blot: This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect human MuSK. The detection limit for rhMuSK is approximately 25 ng/lane under non-reducing and reducing conditions. Direct ELISA: This antibody can be used at 0.5-1.0 μg/mL with the appropriate secondary reagents to detect human MuSK. The detection limit for rhMuSK is approximately 10 ng/well. -
Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- 0.5 mL sterile PBS
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Concentration
- Lot specific
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Buffer
- Lyophilized from PBS, pH 7.4, 5 % trehalose
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze-thaw cycles.
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- MUSK (Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK))
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Alternative Name
- MUSK
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Background
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Name/Gene ID: MUSK
Subfamily: MUSK
Family: Protein Kinase
Synonyms: MUSK, Nsk1, Nsk2, MDK4, Muscle-specific MUSK receptor -
Gene ID
- 4593
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UniProt
- O15146
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Pathways
- RTK Signaling, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development
Target
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