Insulin antibody (C-Term)

Catalog No. ABIN295071

This anti-Insulin antibody is a Mouse Monoclonal antibody detecting Insulin in IHC and ELISA. Suitable for Human.

Quick Overview for Insulin antibody (C-Term) (ABIN295071)

Target: Insulin (INS)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Insulin antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Clone: 8E2

Product Details anti-Insulin Antibody

Binding Specificity: C-Term

Specificity: C-terminal pentapeptide of insulin beta-chain. MAbs 7F8, D4B8, 3A6 and 8E2 react with different antigenic determinants. Kass MAb 7F8 is 7.5 x 109 M-1 Kass MAb D4B8 is 1.5 x 108 M-1 Kass MAb 3A6 is 8.0 x 108 M-1 Kass MAb 8E2 is 6.0 x 108 M-1 Kass MAb C7C9 is 1.0 x 109 M-1 Kass MAb 7F5 is 1.0 x 109 M-1 These antibodies cross-react with human proinsulin, bovine insulin (30 % ) and porcine insulin. No cross-reaction with free C-peptide.

Purification: Protein A purified

Immunogen: Purified human insulin.

Type of Immunogen: Purified protein

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freezing

Storage: 4 °C

Storage Comment: 4°C, avoid freezing.

Target Details for Insulin

Target: Insulin (INS)

Alternative Name: Insulin

Background: Name/Gene ID: INS
Family: Hormone

Synonyms: INS, IRDN, IDDM2, Preproinsulin, ILPR, Insulin, MODY10, Proinsulin

Gene ID: 3630

UniProt: P01308

Pathways: NF-kappaB Signaling, RTK Signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation