BRCA1 antibody (pSer1423)

Catalog No. ABIN7303734

This Rabbit Polyclonal antibody specifically detects BRCA1 in WB, IHC and IF. It exhibits reactivity toward Human, Rat and Monkey.

Quick Overview for BRCA1 antibody (pSer1423) (ABIN7303734)

Target: BRCA1 (Breast Cancer 1 (BRCA1))

Reactivity: Human, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRCA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-BRCA1 Antibody

Binding Specificity: pSer1423

Purpose: Rabbit polyclonal antibody to BRCA1 (Phospho-S1423)

Specificity: Recognizes endogenous levels of BRCA1 protein only when phosphorylated at S1423.

Characteristics: Rabbit polyclonal antibody to BRCA1 (pS1423)

Purification: The antibody was purified by immunogen affinity chromatography.

Immunogen: KLH-conjugated synthetic phosphopeptide corresponding to residues surrounding S1423 of human BRCA1 protein. The exact sequence is proprietary.

Application Details

Application Notes: WB (1/500 - 1/1000), IH (1/100 - 1/200), IF/IC (1/100 - 1/500)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in 0.42 % Potassium phosphate, 0.87 % Sodium chloride, pH 7.3, 30 % glycerol, and 0.01 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

Expiry Date: 12 months

Target Details for BRCA1

Target: BRCA1 (Breast Cancer 1 (BRCA1))

Alternative Name: BRCA1

Background: RNF53, Breast cancer type 1 susceptibility protein, RING finger protein 53

Gene ID: 672, 497672

UniProt: P38398

Pathways: Cell Division Cycle, DNA Damage Repair, Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Response to DNA Damage Stimulus