F12 antibody

Catalog No. ABIN2962710

This Mouse Monoclonal antibody specifically detects F12 in WB, ELISA, IP and ICC. It exhibits reactivity toward Human.

Quick Overview for F12 antibody (ABIN2962710)

Target: F12 (Coagulation Factor XII (F12))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This F12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunocytochemistry (ICC)

Clone: B7C9

Product Details anti-F12 Antibody

Specificity: Reacts with human Factor XII Heavy Chain (KD of 9.8nM) and partially blocks Factor XII activity. Suitable for coagulation assays.

Purification: Purified (protein G)

Immunogen: Purified human Factor XII.

Isotype: IgG1

Application Details

Application Notes: Working dilution: Optimal dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Buffer: PBS, pH 7.4.

Handling Advice: Dilute in PBS or medium that is identical to that used in the assay system.

Storage: -20 °C/-80 °C

Storage Comment: Stable for at least one year at -20°C to -70°C. Avoid multiple freeze-thaw cycles.

Expiry Date: 12 months

Target Details for F12

Target: F12 (Coagulation Factor XII (F12))

Alternative Name: Factor XII Heavy Chain

Background: Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. This single chain zymogen circulates in blood andis converted to a two-chain serine protease with an heavy chain (alpha-factor XIIa) and a light chain wich contains only a catalytic domain.

Coagulation factor XII (EC:3.4.21.38) Hageman factor, HAF Coagulation factor XIIa light chain Beta-factor XIIa part 2 HAE3 HAEX Gene name : F12

Gene ID: 2161

UniProt: P00748

Pathways: Complement System