PKC delta antibody (pSer664)

Catalog No. ABIN2964697

The Rabbit Polyclonal anti-PKC delta antibody has been validated for WB. It is suitable to detect PKC delta in samples from Human and Rat.

Quick Overview for PKC delta antibody (pSer664) (ABIN2964697)

Target: PKC delta (PKCd) (Protein Kinase C, delta (PKCd))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PKC delta antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PKC delta Antibody

Binding Specificity: pSer664

Specificity: Recognizes Human PKCd. Mouse PKCd [pS662] (83 % homologous) has not been tested, but is expected to react. This antibody has been shown to cross-react with rat PKCd [pS662] (83 % homologous) PKCa [pS657] (75 % homologous) and PKCbII [pS660] (67 % homologous) by peptide competition experiments.

Purification: Immunoaffinity purified

Immunogen: Synthetic phosphopeptide derived from a region of human PKC that contains serine 664.

Type of Immunogen: Synthetic phospho-peptide

Application Details

Application Notes: Approved: WB (1:1000)

Usage: Suitable for use in Western Blot. Western Blot: 1:1000. Positive control: K562 cells treated with PMA, a phorbol ester.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS (without Mg2+, Ca2+),  pH 7.2, 1 mg/mL BSA (IgG, protease free), 0.1 % sodium azide, 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for PKC delta

Target: PKC delta (PKCd) (Protein Kinase C, delta (PKCd))

Alternative Name: PRKCD / PKC-Delta

Background: Name/Gene ID: PRKCD
Subfamily: PKC
Family: Protein Kinase

Synonyms: PRKCD, MAY1, NPKC-delta, PKCD, Protein kinase C delta type, Protein kinase C delta VIII, Protein kinase C, delta, Pkcdelta, PKC delta, Protein kinase c delta, Tyrosine-protein kinase PRKCD

Gene ID: 5580

UniProt: Q05655

Pathways: Interferon-gamma Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Myometrial Relaxation and Contraction, M Phase, G-protein mediated Events, Dicarboxylic Acid Transport, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, Lipid Metabolism