NRP2 antibody (AA 150-420)
Quick Overview for NRP2 antibody (AA 150-420) (ABIN3016283)
Target
See all NRP2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 150-420
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Sequence
- SKNFTSPNGT IESPGFPEKY PHNLDCTFTI LAKPKMEIIL QFLIFDLEHD PLQVGEGDCK YDWLDIWDGI PHVGPLIGKY CGTKTPSELR SSTGILSLTF HTDMAVAKDG FSARYYLVHQ EPLENFQCNV PLGMESGRIA NEQISASSTY SDGRWTPQQS RLHGDDNGWT PNLDSNKEYL QVDLRFLTML TAIATQGAIS RETQNGYYVK SYKLEVSTNG EDWMVYRHGK NHKVFQANND ATEVVLNKLH APLLTRFVRI RPQTWHSGIA L
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 150-420 of human NRP2 (NP_003863.2).
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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: "The crucial role of SEMA3F in suppressing the progression of oral squamous cell carcinoma." in: Cellular & molecular biology letters, Vol. 22, pp. 32, (2018) (PubMed).
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- NRP2 (Neuropilin 2 (NRP2))
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Alternative Name
- NRP2
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Background
- This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene.,NRP2,NP2,NPN2,PRO2714,VEGF165R2,neuropilin-2,Neuroscience,Cell Type Marker,Cardiovascular,Angiogenesis,Neuron marker,Growth Cone,NRP2
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Molecular Weight
- 62 kDa/101 kDa/102 kDa/104 kDa
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Gene ID
- 8828
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UniProt
- O60462
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Pathways
- Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
Target
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