Vimentin antibody (AA 1-200)

Catalog No. ABIN3016292

This Rabbit Polyclonal antibody specifically detects Vimentin in WB, IHC and IF. It exhibits reactivity toward Human and has been mentioned in 3+ publications.

Quick Overview for Vimentin antibody (AA 1-200) (ABIN3016292)

Target: Vimentin (VIM)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Vimentin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Vimentin Antibody

Binding Specificity: AA 1-200

Sequence: MSTRSVSSSS YRRMFGGPGT ASRPSSSRSY VTTSTRTYSL GSALRPSTSR SLYASSPGGV YATRSSAVRL RSSVPGVRLL QDSVDFSLAD AINTEFKNTR TNEKVELQEL NDRFANYIDK VRFLEQQNKI LLAELEQLKG QGKSRLGDLY EEEMRELRRQ VDQLTNDKAR VEVERDNLAE DIMRLREKLQ EEMLQREEAE

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human Vimentin (NP_003371.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-Vimentin antibody (ABIN3016292)

Shen, Sun, Sun, Li, Wu, Li, Chen, Liu, Cui, Zhou: "ARRDC3 suppresses colorectal cancer progression through destabilizing the oncoprotein YAP." in: FEBS letters, Vol. 592, Issue 4, pp. 599-609, (2019) (PubMed).

Nie, Huang, Deng, Bao, Liu, Feng, Wang, Chen, Qi, Pan: "The purine receptor P2X7R regulates the release of pro-inflammatory cytokines in human craniopharyngioma." in: Endocrine-related cancer, Vol. 24, Issue 6, pp. 287-296, (2018) (PubMed).

Liu, Wang, Li, Zhang, Peng, Peng, Song, Qi, Pan: "TREM-1 expression in craniopharyngioma and Rathke's cleft cyst: its possible implication for controversial pathology." in: Oncotarget, Vol. 7, Issue 31, pp. 50564-50574, (2018) (PubMed).

Target Details for Vimentin

Target: Vimentin (VIM)

Alternative Name: VIM

Background: This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.,CTRCT30,HEL113,Vimentin,VIM,vimentin,Cancer,Tumor biomarkers,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Intermediate Filaments,Neuroscience,Cell Type Marker,Stem Cells,Neural Stem Cells,Neural Stem Cell marker,VIM

Molecular Weight: 53 kDa

Gene ID: 7431

UniProt: P08670

Pathways: Caspase Cascade in Apoptosis