Aquaporin 4 antibody (AA 244-323)

Catalog No. ABIN3016921

This anti-Aquaporin 4 antibody is a Rabbit Polyclonal antibody detecting Aquaporin 4 in WB, IHC and IF. Suitable for Human.

Quick Overview for Aquaporin 4 antibody (AA 244-323) (ABIN3016921)

Target: Aquaporin 4 (AQP4)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aquaporin 4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Aquaporin 4 Antibody

Binding Specificity: AA 244-323

Sequence: AGGLYEYVFC PDVEFKRRFK EAFSKAAQQT KGSYMEVEDN RSQVETDDLI LKPGVVHVID VDRGEEKKGK DQSGEVLSSV

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 244-323 of human Aquaporin-4 (AQP4) (NP_001641.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Aquaporin 4

Target: Aquaporin 4 (AQP4)

Alternative Name: AQP4

Background: This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. This protein is the predominant aquaporin found in brain and has an important role in brain water homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.,AQP4,MIWC,WCH4,aquaporin-4,Cancer,Signal Transduction,Endocrine & Metabolism,Neuroscience,Neurodegenerative Diseases Markers,Other Neurological disorders,AQP4

Molecular Weight: 32 kDa/34 kDa

Gene ID: 361

UniProt: P55087

Pathways: Sensory Perception of Sound