Aquaporin 4 antibody

Catalog No. ABIN7201263

The Mouse Monoclonal anti-Aquaporin 4 antibody is suitable to detect Aquaporin 4 in samples from Human, Mouse and Rat. It has been validated for WB, IHC and IF.

Quick Overview for Aquaporin 4 antibody (ABIN7201263)

Target: Aquaporin 4 (AQP4)

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This Aquaporin 4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Aquaporin 4 Antibody

Purpose: Mouse Anti-Aquaporin 4 Monoclonal Antibody

Specificity: The antibody detects endogenous Aquaporin 4 proteins.

Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Immunogen: Synthetic Peptide

Isotype: IgG1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:1000,IF 1:100-200,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.5 % BSA, 0.02 % sodium azide as Preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Aquaporin 4

Target: Aquaporin 4 (AQP4)

Alternative Name: Aquaporin 4

Background: AQP4, Aquaporin-4, AQP-4, Mercurial-insensitive water channel, MIWC, WCH4AQP4 encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. Aquaporin 4 is the predominant aquaporin found in brain and has an important role in brain water homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for AQP4. A recent study provided evidence for translational readthrough in AQP4 and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.

Molecular Weight: 48kD

Gene ID: 361

UniProt: P55087

Pathways: Sensory Perception of Sound