HNF1A antibody
Quick Overview for HNF1A antibody (ABIN3017356)
Target
See all HNF1A AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- A synthetic peptide of human HNF1A
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:100
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- HNF1A (HNF1 Homeobox A (HNF1A))
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Alternative Name
- HNF1A
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Background
- The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms.,HNF1A,HNF-1A,HNF1,IDDM20,LFB1,MODY3,TCF-1,TCF1,Epigenetics & Nuclear Signaling,Transcription Factors,Cell Biology & Developmental Biology,Cell Adhesion,Wnt/β-Catenin Signaling Pathway,HNF1A
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Molecular Weight
- 12 kDa/27 kDa/30 kDa/43 kDa/55-70 kDa
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Gene ID
- 6927
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UniProt
- P20823
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Pathways
- Hormone Transport, Carbohydrate Homeostasis
Target
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