kappa Light Chain antibody (PE)

Catalog No. ABIN302034

Cited in 3+ publications. The PE-conjugated Mouse Monoclonal anti-kappa Light Chain antibody (Clone A8B5) (ABIN302034) specifically detects kappa Light Chain in FACS. The antibody is reactive with Human samples.

Quick Overview for kappa Light Chain antibody (PE) (ABIN302034)

Target: kappa Light Chain

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This kappa Light Chain antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: A8B5

Product Details anti-kappa Light Chain Antibody (PE)

Purpose: Anti-Hu Ig Kappa Light Chain PE

No Cross-Reactivity: Goat, Guinea Pig, Hamster, Rabbit, Sheep

Cross-Reactivity (Details): Human

Characteristics: The mouse monoclonal antibody A8B5 reacts with kappa light chains (22.5 kDa) of immunoglobulins.

Purification: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Isotype: IgG1

Application Details

Application Notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze,Protect from prolonged exposure to light

Storage: 4 °C

Storage Comment: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

References for anti-kappa Light Chain antibody (PE) (ABIN302034)

Scheeren, Diehl, Smit, Beaumont, Naspetti, Bende, Blom, Karube, Ohshima, van Noesel, Spits: "IL-21 is expressed in Hodgkin lymphoma and activates STAT5: evidence that activated STAT5 is required for Hodgkin lymphomagenesis." in: Blood, Vol. 111, Issue 9, pp. 4706-15, (2008) (PubMed).

Diaz de Domingo, Lardo, Romero Artaza, Merelli, Carbia, Sánchez Avalos: "[Immunocytochemistry techniques for the diagnosis of hematologic neoplasms]." in: Medicina, Vol. 59, Issue 1, pp. 11-6, (1999) (PubMed).

Konig, Wennemuth, Soyer, Hoffmann, Happle, Krause: "Vulvar amyloidosis mimicking giant condylomata acuminata in a patient with multiple myeloma." in: European journal of dermatology : EJD, Vol. 9, Issue 1, pp. 29-31, (1999) (PubMed).

Target Details for kappa Light Chain

Target: kappa Light Chain

Alternative Name: Ig Kappa Light Chain

Background: Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five heavy chains types) and two light chains (kappa, lambda, both having a molecular weight of 22.5 kDa). Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30.,Immunoglobulin kappa, Igk

Gene ID: 35